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  2. Raynaud syndrome - Wikipedia

    en.wikipedia.org/wiki/Raynaud_syndrome

    A more recent treatment for severe Raynaud's is the use of botulinum toxin. The 2009 article [37] studied 19 patients ranging in age from 15 to 72 years with severe Raynaud's phenomenon of which 16 patients (84%) reported pain reduction at rest; 13 patients reported immediate pain relief, three more had gradual pain reduction over 1–2 months ...

  3. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.

  4. Intermittent claudication - Wikipedia

    en.wikipedia.org/wiki/Intermittent_claudication

    Intermittent claudication, also known as vascular claudication, is a symptom that describes muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), [1] classically in the calf muscle, which occurs during exercise, such as walking, and is relieved by a short period of rest.

  5. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Cardiovascular: Raynaud's phenomenon (is the presenting symptom in 30% of affected persons, occurs in 95% of affected individuals at some time during their illness); healed pitting ulcers on the fingertips; skin and mucosal telangiectasis; palpitations, irregular heart rate and fainting due to conduction abnormalities, hypertension, and ...

  6. Mixed connective tissue disease - Wikipedia

    en.wikipedia.org/wiki/Mixed_connective_tissue...

    The most prevalent skin change is Raynaud's phenomenon, which usually appears early in the course of the disease. [14] Swollen digits are a common sign, and on occasion, the complete hand swells. [15] [16] Acrosclerosis, also known as sclerodactyly, can develop with or without proximal scleroderma and is usually a later symptom of the condition ...

  7. Largest ever genetic study of Raynaud's phenomenon ... - AOL

    www.aol.com/news/study-pinpoints-genes-behind...

    In people with Raynaud’s phenomenon, cold temperatures or stress trigger spasms in the small blood vessels near the surface of the skin, causing the vessels to constrict and limit blood flow.

  8. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.

  9. Rare disorder can turn fingers and toes white or blue when it ...

    www.aol.com/lifestyle/rare-disorder-turn-fingers...

    Secondary Raynaud’s — also known as Raynaud's phenomenon — happens because of an underlying disease or other factor. Most scleroderma patients develop it, for example, Makol says.