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  2. Rectal administration - Wikipedia

    en.wikipedia.org/wiki/Rectal_administration

    The reasons for rectal administration are largely the same as with medicinal drugs: Bypassing the first-pass effect, fast onset, and a relatively high bioavailability with some drugs. [ 7 ] Rectal administration is sometimes thought of as a safer alternative to intravenous injection of psychoactive substances, [ 8 ] which carries a significant ...

  3. Preparation H - Wikipedia

    en.wikipedia.org/wiki/Preparation_H

    The Canadian formulation of Preparation H includes a yeast extract called Biodyne which was removed in 1995 from the formulation sold in the United States. This yeast extract was the primary ingredient of the original formulation by inventor George Sperti , [ 5 ] [ 6 ] and Pfizer believes that it removes wrinkles from skin and heals dry ...

  4. Laxative - Wikipedia

    en.wikipedia.org/wiki/Laxative

    Glycerin suppositories used as laxatives. Laxatives, purgatives, or aperients are substances that loosen stools [1] and increase bowel movements. They are used to treat and prevent constipation. Laxatives vary as to how they work and the side effects they may have.

  5. NYT ‘Connections’ Hints and Answers Today, Friday, December 13

    www.aol.com/nyt-connections-hints-answers-today...

    Read no further until you really want some clues or you've completely given up and want the answers ASAP. Get ready for all of today's NYT 'Connections’ hints and answers for #551 on Friday ...

  6. Fecal impaction - Wikipedia

    en.wikipedia.org/wiki/Fecal_impaction

    Enemas (such as hyperosmotic saline) and suppositories (such as glycerine suppositories) work by increasing water content and stimulating peristalsis to aid in expulsion, and both work much more quickly than oral laxatives. Because enemas work in 2–15 minutes, they do not allow sufficient time for a large fecal mass to soften.

  7. Suppository - Wikipedia

    en.wikipedia.org/wiki/Suppository

    A suppository is a dosage form used to deliver medications by insertion into a body orifice (any opening in the body), where it dissolves or melts to exert local or systemic effects. There are three types of suppositories, each to insert into a different sections: rectal suppositories into the rectum , vaginal suppositories into the vagina ...

  8. New York tax preparer 'the Magician' pleads guilty to filing ...

    www.aol.com/york-tax-preparer-magician-pleads...

    Federal prosecutors announced Tuesday that a New York tax preparer known as 'the Magician" pled guilty to filing thousands of false tax returns.

  9. Macrogol - Wikipedia

    en.wikipedia.org/wiki/Macrogol

    Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...

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