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What Is Acid Reflux? Your stomach contents are meant to only flow one way—downward. But sometimes, food flows back into the esophagus. That’s acid reflux.1. Why does it happen? Normally, the ...
Gastric acid or stomach acid is the acidic component – hydrochloric acid of gastric juice, produced by parietal cells in the gastric glands of the stomach lining. With a pH of between one and three, gastric acid plays a key role in the digestion of proteins by activating digestive enzymes , which together break down the long chains of amino ...
Acid reflux, also known as gastroesophageal reflux disease, is a common condition that causes acid to splash from the stomach into the esophagus. The result: telltale symptoms of chest pain ...
The following are enzymes produced by the stomach and their respective function: Pepsin is the main gastric enzyme. It is produced in the stomach by gastric chief cells in its inactive form pepsinogen, which is a zymogen. Pepsinogen is then activated by the stomach acid into its active form, pepsin.
Heartburn, also known as pyrosis, cardialgia or acid indigestion, [2] is a burning sensation in the central chest or upper central abdomen. [ 3 ] [ 4 ] [ 5 ] Heartburn is usually due to regurgitation of gastric acid (gastric reflux) into the esophagus .
Parietal cells (also known as oxyntic cells) are epithelial cells in the stomach that secrete hydrochloric acid (HCl) and intrinsic factor.These cells are located in the gastric glands found in the lining of the fundus and body regions of the stomach. [1]
The gastric mucosa is covered in surface mucous cells that produce the mucus necessary to protect the stomach's epithelial lining from gastric acid secreted by parietal cells in the glands, and from pepsin, a secreted digestive enzyme. Surface mucous cells follow the indentations and partly line the gastric pits.
Mucosal disruption in acid peptic disease patients can be caused by infection, barrier disruption, or gastric acid hypersecretion.Acid peptic diseases can arise due to various risk factors such as Helicobacter pylori infection, alcoholism, tobacco use, cocaine and amphetamine use, nonsteroidal anti-inflammatory drug use (NSAIDs), fasting, Zollinger-Ellison syndrome, angiogenesis inhibitor ...
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