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The distal convoluted tubule (DCT) is a portion of kidney nephron between the loop of Henle and the collecting tubule. ... the distal convoluted tubule cells, ...
The distal convoluted tubule has a different structure and function to that of the proximal convoluted tubule. Cells lining the tubule have numerous mitochondria to produce enough energy for active transport to take place. Much of the ion transport taking place in the distal convoluted tubule is regulated by the endocrine system.
This illustration demonstrates the normal kidney physiology, including the Proximal Convoluted Tubule (PCT), Loop of Henle, and Distal Convoluted Tubule (DCT). It also includes illustrations showing where some types of diuretics act, and what they do. Renal physiology (Latin renes, "kidneys") is the study of the physiology of the kidney.
In the kidney, the loop of Henle (English: / ˈ h ɛ n l i /) (or Henle's loop, Henle loop, [1] nephron loop [2] or its Latin counterpart ansa nephroni) is the portion of a nephron that leads from the proximal convoluted tubule to the distal convoluted tubule.
It is adjacent to the distal convoluted tubule, the most distal segment of the renal tubule. Connecting tubules from several adjacent nephrons merge to form cortical collecting tubules, and these may join to form cortical collecting ducts (CCD). [1] Connecting tubules of some juxtamedullary nephrons may arch upward, forming an arcade. It is ...
The sodium-chloride symporter (also known as Na +-Cl − cotransporter, NCC or NCCT, or as the thiazide-sensitive Na +-Cl − cotransporter or TSC) is a cotransporter in the kidney which has the function of reabsorbing sodium and chloride ions from the tubular fluid into the cells of the distal convoluted tubule of the nephron.
Urinary casts are microscopic cylindrical structures produced by the kidney and present in the urine in certain disease states. They form in the distal convoluted tubule and collecting ducts of nephrons, then dislodge and pass into the urine, where they can be detected by microscopy.
Early distal convoluted tubule: Na +, Cl −: PTH causes Ca 2+ reabsorption. Collecting tubules: Na + (3–5%), H 2 O: Na + is reabsorbed in exchange for K +, and H +, which is regulated by aldosterone. ADH acts on the V2 receptor and inserts aquaporins on the luminal side