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Pantoprazole, sold under the brand name Protonix, among others, is a medication used for the treatment of stomach ulcers, short-term treatment of erosive esophagitis due to gastroesophageal reflux disease (GERD), maintenance of healing of erosive esophagitis, and pathological hypersecretory conditions including Zollinger–Ellison syndrome.
Proton-pump inhibitors (PPIs) are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H + /K + ATPase proton pump. [1]
Pantoprazole was first prepared in April 1985 by a small group of scale-up chemists. It is a dimethoxy-substituted pyridine bound to a fluoroalkoxy substituted benzimidazole. [5] Pantoprazole sodium is available as gastroresistant or delayed release tablets and as lyophilized powder for intravenous use.
This route is occasionally used for drugs and fluids in emergency medicine and pediatrics when intravenous access is difficult. Intraperitoneal, (infusion or injection into the peritoneum) e.g. peritoneal dialysis. Intrathecal (into the spinal canal) is most commonly used for spinal anesthesia and chemotherapy. Intrauterine.
The tension between wanting to stay put vs. being antsy for more can be a real deal-breaker. Most Compatible Sign: Aries These two fire signs burn more brightly together. They both share that ...
Guidance should also be provided to the clinical investigator on the recognition and treatment of possible overdose and adverse drug reactions that is based on previous human experience and on the pharmacology of the investigational product". [2] The sponsor is responsible for keeping the information in the IB up-to-date.
Just before the College Football Playoff kicks off, Dan Wetzel, Ross Dellenger, and SI's Forde provide a final preview of the 12-team bracket. They discuss the potential for five to six different ...
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