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Alternatively, one could group subjects based on their body mass index (BMI) and compare their risk of developing heart disease or cancer. Prospective cohort studies are typically ranked higher in the hierarchy of evidence than retrospective cohort studies [3] and can be more expensive than a case–control study. [4]
A cohort of individuals that share a common exposure factor is compared with another group of equivalent individuals not exposed to that factor, to determine the factor's influence on the incidence of a condition such as disease or death. Retrospective cohort studies have existed for approximately as long as prospective cohort studies. [1]
A "prospective cohort" defines the groups before the study is done, while historical studies, which are sometimes referred to as "retrospective cohort", define the grouping after the data is collected. Examples of a retrospective cohort are Long-Term Mortality after Gastric Bypass Surgery [13] and The Lothian Birth Cohort Studies. [14]
Retrospective Cohort Study: Retrospective Studies start with subjects that are at risk to have the outcome or disease of interest and identifies the outcome starting from where the subject is when the study starts to the past of the subject to identify the exposure. Retrospective use records: clinical, educational, birth certificates, death ...
Prospective studies usually have fewer potential sources of bias and confounding than retrospective studies. [ 7 ] A retrospective study, on the other hand, looks backwards and examines exposures to suspected risk or protection factors in relation to an outcome that is established at the start of the study.
Prospective refers to an event that is likely or expected to happen in the future. For example, a prospective student is someone who is considering attending a school. A prospective cohort study is a type of study, e.g., in sociology or medicine, that follows participants for a particular future time period.
Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...
Cohort Canada – 5,000 Various studies, managed by the Data Center Studies on Congenital Heart Diseases Copenhagen General Population Study (CGPS) Cohort Denmark 1976 170,000 The study is an ongoing prospective cohort study, that investigates the epidemiology of a wide range of diseases in a representative sample of the Danish population. Now ...