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Among the available prescription drugs, the evidence is best for terbinafine and naftifine, but other agents may also work. [7] Topical antifungals are applied to the lesion twice a day for at least 3 weeks. The lesion usually resolves within 2 weeks, but therapy should be continued for another week to ensure the fungus is completely eradicated.
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin [2] (a dermatomycosis), that may affect skin, hair, and nails. [1] Typically it results in a red, itchy, scaly, circular rash. [ 1 ]
Treatment of tinea capitis requires an oral antifungal agent; griseofulvin is the most commonly used drug, but other newer antimycotic drugs, such as terbinafine, itraconazole, and fluconazole have started to gain acceptance, topical treatment include selenium sulfide shampoo.
The side effects of oral treatment are significant and people without an infection should not take these drugs. [36] Azoles are the group of antifungals which act on the cell membrane of fungi. They inhibit the enzyme 14-alpha-sterol demethylase, a microsomal CYP, which is required for the biosynthesis of ergosterol for the cytoplasmic membrane.
Topical clotrimazole is usually not effective in the treatment of fungal infections of the scalp or nails. [citation needed] When using over-the-counter drug clotrimazole products, use should be discontinued if the condition does not improve after treatment for 2 weeks for jock itch or after 4 weeks for athlete's foot or ringworm. [9]
Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [1] [2] [3] It is either taken by mouth or applied to the skin as a cream or ointment.
In fact, when it comes to toenail fungus, oral prescription terbinafine is considered the most effective treatment. That said, the terbinafine in topical antifungals doesn't have the same effect ...
Griseofulvin is an antifungal medication used to treat a number of types of dermatophytoses (ringworm). [1] This includes fungal infections of the nails and scalp, as well as the skin when antifungal creams have not worked. [2] It is taken by mouth. [1]