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A scanner used to measure bone density using dual energy X-ray absorptiometry. Bone density, or bone mineral density, is the amount of bone mineral in bone tissue.The concept is of mass of mineral per volume of bone (relating to density in the physics sense), although clinically it is measured by proxy according to optical density per square centimetre of bone surface upon imaging. [1]
Researchers from Johns Hopkins University School of Medicine in Baltimore, MD, showed that total body bone mass and density both decreased in adults over the age of 65 who received levothyroxine ...
Single photon absorption is the earliest method to measure bone mineral density accurately. Its basic principle is that bone mineral density can be obtained by the law of absorption. In this law, the important parameters to be obtained are bone thickness, bone absorption coefficient and radiation intensity (or counting) after bone absorption.
A wide variety of body composition measurement methods exist. The gold standard measurement technique for the 4-compartment model consists of a weight measurement, body density measurement using hydrostatic weighing or air displacement plethysmography, total body water calculation using isotope dilution analysis, and mineral content measurement by dual-energy X-ray absorptiometry (DEXA). [1]
The bone mass in the skeleton makes up about 14% of the total body weight (ca. 10–11 kg for an average person) and reaches maximum mass between the ages of 25 and 30. [2] The human skeleton can be divided into the axial skeleton and the appendicular skeleton.
DXA is only able to provide the areal bone mineral density. High-resolution peripheral quantitative computed tomography (HR-pQCT) is better than DXA at detecting bone microarchitecture, modeling whole-bone geometry using 3-dimensional information from scans. This method allows estimation of bone strength and other mechanical properties. [20]
Peak bone mass is the maximum amount of bone a person has during their life. [1] It typically occurs in the early 20s in females and late 20s in males. [2] Peak bone mass is typically lower in females than males, and is also lower in White people and Asians compared to black populations. [1]
Optimal bone health is characterized by adequate bone mineral density (BMD) and proper bone microarchitecture, which together contribute to bone strength. [2] Osteoporosis, a skeletal disorder characterized by compromised bone strength and increased risk of fractures, is a major concern in bone health, particularly among older adults.