Search results
Results from the WOW.Com Content Network
riboswitch gene finders, i.e. systems aimed at uncovering riboswitches by genomic inspections, mostly based on motif-searching mechanisms. This group contains Infernal, the founding component of the Rfam database, [ 32 ] and more specific tools such as RibEx [ 33 ] or RiboSW.
The TPP riboswitch, also known as the THI element and Thi-box riboswitch, is a highly conserved RNA secondary structure. It serves as a riboswitch [1][2] that binds thiamine pyrophosphate (TPP) directly and modulates gene expression through a variety of mechanisms in archaea, bacteria and eukaryotes. [3][4][5] TPP is the active form of thiamine ...
The nhaA-I RNA motif is a conserved RNA structure that was discovered by bioinformatics. [1] nhaA -I motif RNAs are found in Acidobacteriota, alpha-, beta- and Gammaproteobacteria, Verrucomicrobiota and the tentative phylum NC10 (see bacterial phyla and List of taxa with candidatus status ). nhaA -I motif RNAs likely function as cis-regulatory ...
T-box leader. Usually found in gram-positive bacteria, the T box leader sequence is an RNA element that controls gene expression through the regulation of translation by binding directly to a specific tRNA and sensing its aminoacylation state. [ 1] This interaction controls expression of downstream aminoacyl-tRNA synthetase genes, amino acid ...
PDBe. The fluoride riboswitch (formerly called the crcB RNA motif) is a conserved RNA structure identified by bioinformatics in a wide variety of bacteria and archaea. [1] These RNAs were later shown to function as riboswitches that sense fluoride ions. [2] These "fluoride riboswitches" increase expression of downstream genes when fluoride ...
Ribozyme. 3D structure of a hammerhead ribozyme. Ribozymes (ribo nucleic acid en zyme s) are RNA molecules that have the ability to catalyze specific biochemical reactions, including RNA splicing in gene expression, similar to the action of protein enzymes. The 1982 discovery of ribozymes demonstrated that RNA can be both genetic material (like ...
A purine riboswitch is a sequence of ribonucleotides in certain messenger RNA (mRNA) that selectively binds to purine ligands via a natural aptamer domain. [1] This binding causes a conformational change in the mRNA that can affect translation by revealing an expression platform for a downstream gene, or by forming a translation-terminating stem-loop.
The Moco RNA motif is a conserved RNA structure [1] that is presumed to be a riboswitch that binds molybdenum cofactor or the related tungsten cofactor. Genetic experiments support the hypothesis that the Moco RNA motif corresponds to a genetic control element that responds to changing concentrations of molybdenum or tungsten cofactor. [2]