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CLL is a type of cancer that affects the bone marrow and blood, causing too many lymphocytes to be produced. It usually affects older people and has no symptoms in early stages, but can lead to infections, anemia, and bone marrow failure.
Leukemia is a group of blood cancers that produce abnormal blood cells and affect the bone marrow and immune system. Learn about the four main types of leukemia (acute and chronic lymphocytic and myeloid), their causes, symptoms, diagnosis, treatment, and prognosis.
Richter's transformation (RT) is the conversion of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) into a more aggressive disease, such as diffuse large B-cell lymphoma (DLBCL) or Hodgkin's lymphoma (HL). RT is rare, occurs in 1-10% of CLL/SLL cases, and has a poor prognosis.
Leukemoid reaction is a high white blood cell count due to stress or infection, not a blood cancer. Learn how to distinguish it from chronic myelogenous leukemia (CML) by testing for the Philadelphia chromosome or BCR/ABL gene.
A medical laboratory test that measures the types and amounts of white blood cells in a person's blood. The test can aid in the diagnosis of infections and blood disorders, and is performed by automated or manual methods.
CMML is a type of leukemia that shows characteristics of both myelodysplastic syndromes and myeloproliferative neoplasms. It is diagnosed by increased monocytes, dysplasia, abnormal cells and no Philadelphia chromosome or PDGFRA/B gene mutations.
Paraneoplastic syndrome is a rare condition caused by a tumor producing chemical signaling molecules or triggering an immune response. It can affect various systems, such as endocrine, neurological, mucocutaneous, and hematological, and may precede or accompany the diagnosis of cancer.
Lymphoid leukemia is a group of cancers affecting white blood cells called lymphocytes. Learn about the types, causes, symptoms, diagnosis and treatment of lymphoid leukemia, as well as the differences between lymphoid and myeloid leukemia.