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The causes of frontal lobe disorders can be closed head injury. An example of this can be from an accident, which can cause damage to the orbitofrontal cortex area of the brain. [2] Cerebrovascular disease may cause a stroke in the frontal lobe. Tumours such as meningiomas may present with a frontal lobe syndrome. [11]
Damage to the frontal lobe can cause increased irritability, which may include a change in mood and an inability to regulate behavior. [1] Particularly, an injury of the frontal lobe could lead to deficits in executive function , such as anticipation, goal selection, planning, initiation, sequencing, monitoring (detecting errors), and self ...
The most frequent cause of the syndrome is brain damage to the frontal lobe. Brain damage leading to the dysexecutive pattern of symptoms can result from physical trauma such as a blow to the head or a stroke [6] or other internal trauma. It is important to note that frontal lobe damage is not the only cause of the syndrome.
Frontal release signs are primitive reflexes traditionally held to be a sign of disorders that affect the frontal lobes. The appearance of such signs reflects the area of brain dysfunction rather than a specific disorder which may be diffuse, such as a dementia, or localised, such as a tumor.
In most cases of executive dysfunction, deficits are attributed to either frontal lobe damage or dysfunction, or to disruption in fronto-subcortical connectivity. [1] Neuroimaging with PET and fMRI has confirmed the relationship between executive function and functional frontal pathology. [ 1 ]
Akinetic mutism can occur in the frontal region of the brain and occurs because of bilateral frontal lobe damage. Akinetic mutism as a result of frontal lobe damage is clinically characterized as hyperpathic. [5] It occurs in patients with bilateral circulatory disturbances in the supply area of the anterior cerebral artery. [2]
Bruns apraxia, or frontal ataxia, is a gait apraxia [1] found in patients with bilateral frontal lobe disorders.It is characterised by an inability to initiate the process of walking, despite the power and coordination of the legs being normal when tested in the seated or lying position.
The frontal lobe has a significant function in attention regulation. Therefore, patients with frontal lobe epilepsy are often found to be co-morbid for another disease called attention-deficit hyperactivity disorder (ADHD), which has a higher prevalence in children. This adds to the various cognitive and behavioral challenges, that they already ...