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Azithromycin is an azalide, a type of macrolide antibiotic. [10] It works by decreasing the production of protein, thereby stopping bacterial growth. [10] [13] Azithromycin was discovered in Yugoslavia (present day Croatia) in 1980 by the pharmaceutical company Pliva and approved for medical use in 1988.
If doxycycline was prescribed as initial therapy, give azithromycin 500 mg or 1 gram for the first day, then give azithromycin 250 mg once daily for 4 days plus metronidazole 400 – 500 mg twice daily for 5 days; If azithromycin was prescribed as initial therapy, then give doxycycline 100 mg twice daily for 7 days plus metronidazole 400 ...
Azithromycin is the most common first-line treatment, but the commonly-used 1 gram single-dose azithromycin treatment can lead to the bacteria commonly developing resistance to azithromycin. [21] An alternative five-day treatment with azithromycin showed no development of antimicrobial resistance. [22] Efficacy of azithromycin against M ...
The five-day treatment with azithromycin showed no development of antimicrobial resistance. [49] Based on these findings, UK doctors are moving to the 5-day azithromycin regimen. Doxycycline is also still used, and moxifloxacin is used as a second-line treatment in case doxycyline and azithromycin are not able to eradicate the infection.
Azithromycin (single oral dose of 20 mg/kg) or topical tetracycline (1% eye ointment twice a day for six weeks). Azithromycin is preferred because it is used as a single oral dose. Although it is expensive, it is generally used as part of the international donation program organized by Pfizer. [6]
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Ceftriaxone by injection and azithromycin by mouth [4] [5] ... others until at least one week past the final day of treatment in order ... was 113. 5 per 100,000 ...
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