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BCL11A is highly expressed in several hematopoietic lineages, and plays a role in the switch from γ- to β-globin expression during the fetal to adult erythropoiesis transition. [ 9 ] Furthermore, BCL11A is expressed in the brain, where it forms a protein complex with CASK to regulate axon outgrowth and branching. [ 10 ]
B-cell CLL/lymphoma refers to a family of genes associated with certain types of lymphoma and leukemia.. Although named for B-cell chronic lymphocytic leukemia, they can be associated with other malignancies.
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies.The specific function of this gene has not yet been determined, but it could also be involved in some malignancies.
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According to the New York Times, here's exactly how to play Strands: Find theme words to fill the board. Theme words stay highlighted in blue when found.
A major cold blast is in store for millions of Americans as a lobe of a polar vortex will bring brutally cold temperatures to nearly every American east of the Rockies.
An Oregon man was arrested and charged Thursday for the murder of a car dealership owner who disappeared three years ago, police said Monday. Murphy Henry, 54, was also charged with abuse of a ...
In addition HbF levels are influenced by polymorphisms in the BCL11A gene [3] and in the MYB gene enhancer. [4] In HPFH the percentage of HbF varies from 0.8-1.0% to about 30% of the total hemoglobin, but levels as high as 100% can be seen in homozygotes for delta beta thalassemia. [citation needed]