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Melting point: 96 °C (205 °F; 369 K) [1] ... 1 H NMR spectrum for N-methylmaleimide. References This page was last edited on 2 September 2024, at 08:50 ...
Maleimide-mediated methodologies are among the most used in bioconjugation. [5] [6] Due to fast reactions and high selectivity towards cysteine residues in proteins, a large variety of maleimide heterobifunctional reagents are used for the preparation of targeted therapeutics, assemblies for studying proteins in their biological context, protein-based microarrays, or proteins immobilisation. [7]
N-Ethylmaleimide (NEM) is an organic compound that is derived from maleic acid. It contains the amide functional group , but more importantly it is an alkene that is reactive toward thiols and is commonly used to modify cysteine residues in proteins and peptides .
N-Methylmaleimide This page was last edited on 17 March 2021, at 20:13 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 License ...
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The chemical reactions of dimethylacetamide are typical of N,N-disubstituted amides. Hydrolysis of the acyl-N bond occurs in the presence of acids: CH 3 CON(CH 3) 2 + H 2 O + HCl → CH 3 COOH + (CH 3) 2 NH 2 + Cl −. However, it is resistant to bases. For this reason DMA is a useful solvent for reactions involving strong bases such as sodium ...
N-Methylmorpholine is the organic compound with the formula O(CH 2 CH 2) 2 NCH 3. It is a colorless liquid. It is a cyclic tertiary amine. It is used as a base catalyst for generation of polyurethanes and other reactions. It is produced by the reaction of methylamine and diethylene glycol as well as by the hydrogenolysis of N-formylmorpholine. [2]
Melting point: 2 to 3 °C (36 to 37 °F; 275 to 276 K) Boiling point: 210 °C (410 °F; 483 K) Solubility in water. Miscible Vapor pressure: 0.08 mmHg at 20 °C