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  2. Paracetamol poisoning - Wikipedia

    en.wikipedia.org/wiki/Paracetamol_poisoning

    In these cases, it has been suggested that the toxic metabolite is produced more in the kidneys than in the liver. [ 15 ] The third phase follows at 3 to 5 days, and is marked by complications of massive liver necrosis leading to fulminant liver failure with complications of coagulation defects, low blood sugar , kidney failure, hepatic ...

  3. Here's how Tylenol holds up against other common pain relievers

    www.aol.com/heres-tylenol-holds-against-other...

    The recommended dose of Tylenol for adults is 325 to 650 milligrams every four to six hours. You should not have more than 3,000 to 4,000 milligrams of Tylenol in a span of 24 hours, recommends Walia.

  4. Analgesic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Analgesic_nephropathy

    The scarring of the small blood vessels, called capillary sclerosis, is the initial lesion of analgesic nephropathy. [7] Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.

  5. Paracetamol - Wikipedia

    en.wikipedia.org/wiki/Paracetamol

    Paracetamol, [a] or acetaminophen, [b] is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain. [13] [14] [15] It is a widely available over-the-counter drug sold under various brand names, including Tylenol and Panadol. Paracetamol relieves pain in both acute mild migraine and episodic tension headache.

  6. Rumack–Matthew nomogram - Wikipedia

    en.wikipedia.org/wiki/Rumack–Matthew_nomogram

    The Rumack–Matthew nomogram, also known as the acetaminophen nomogram, is an acetaminophen toxicity nomogram. It plots serum concentration of acetaminophen against the time since ingestion, in order to predict possible liver toxicity and allow a clinician to decide whether to proceed with N-Acetylcysteine (NAC) treatment.

  7. Hydrocodone/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Hydrocodone/paracetamol

    The panel also cited concerns of liver damage from their paracetamol component, which is also the main ingredient in commonly used nonprescription drugs such as Tylenol. [21] Each year, paracetamol overdose is linked to about 400 deaths and 42,000 hospitalizations.

  8. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses (e.g. acetaminophen, paracetamol) and sometimes even when introduced within therapeutic ranges (e.g. halothane), may injure the organ.

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