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  2. Electrophysiological techniques for clinical diagnosis

    en.wikipedia.org/wiki/Electrophysiological...

    The demyelination and scarring of axons in the neurons of the nervous system can affect their conduction properties and seriously harm the normal communication of the brain with the rest of the body. Multiple sclerosis (MS) is a disease that causes this deterioration of the myelin sheath. There isn't a unique test to diagnose MS and several ...

  3. Biomarkers of multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Biomarkers_of_multiple...

    The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease. [67] The importance of this discovery is that the expression of these genes appears in blood and can be measured by a simple blood analysis. NR1H3 Mutation.

  4. Electrodiagnostic medicine - Wikipedia

    en.wikipedia.org/wiki/Electrodiagnostic_medicine

    More uncommon diseases include ALS, myasthenia gravis, and chronic inflammatory demyelinating polyneuropathy. Using their broader training, physicians in electrodiagnostic medicine, often perform more detailed evaluations which may include laboratory tests, CT or MRI scans, genetic evaluation, biopsy of nerve, skin, or muscle, or perform ...

  5. Electromyography - Wikipedia

    en.wikipedia.org/wiki/Electromyography

    Nerve conduction testing is also often done at the same time as an EMG to diagnose neurological diseases. [24] Some patients can find the procedure somewhat painful, whereas others experience only a small amount of discomfort when the needle is inserted. The muscle or muscles being tested may be slightly sore for a day or two after the ...

  6. Electromyoneurography - Wikipedia

    en.wikipedia.org/wiki/Electromyoneurography

    While interpretation of the results requires background knowledge, irregular data can be used to diagnose many diseases. If the activity of the nerves at rest is abnormal, this may indicate nerve lesion, radiculopathy, or lower motor nerve degeneration. The amplitude or duration of the potential spike may also be used to gather information.

  7. Sporadic late-onset nemaline myopathy - Wikipedia

    en.wikipedia.org/wiki/Sporadic_late-onset...

    [3] [4] The diagnosis of the disease rests on subacutely evolving weakness after age 40, normal to low CK level, a myopathic EMG with fibrillations, and often a monoclonal gammopathy. The diagnosis is confirmed by visualizing rods in cryosections on light and electron microscopy. The associated monoclonal gammopathy has an unfavorable prognosis.

  8. Pathology of multiple sclerosis - Wikipedia

    en.wikipedia.org/.../Pathology_of_multiple_sclerosis

    This is why symptoms can vary greatly between different individuals, depending on where their lesions occur. Repair processes, called remyelination, also play an important role in MS. Remyelination is one of the reasons why, especially in early phases of the disease, symptoms tend to decrease or disappear temporarily.

  9. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

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