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Lead time bias happens when survival time appears longer because diagnosis was done earlier (for instance, by screening), irrespective of whether the patient lived longer. Lead time is the duration of time between the detection of a disease (by screening or based on new experimental criteria) and its usual clinical presentation and diagnosis ...
Length time bias in cancer screening. Screening appears to lead to better survival even when actually no one lived any longer. Length time bias (or length bias) is an overestimation of survival duration due to the relative excess of cases detected that are asymptomatically slowly progressing, while fast progressing cases are detected after giving symptoms.
In psychology and cognitive science, a memory bias is a cognitive bias that either enhances or impairs the recall of a memory (either the chances that the memory will be recalled at all, or the amount of time it takes for it to be recalled, or both), or that alters the content of a reported memory. There are many types of memory bias, including:
Length time bias leads to better perceived survival with screening, even if the course of the disease is not altered. Many screening tests involve the detection of cancers. Screening is more likely to detect slower-growing tumors (due to longer pre-clinical sojourn time) that are less likely to cause harm.
Biases that affect memory, [18] such as consistency bias (remembering one's past attitudes and behavior as more similar to one's present attitudes). Biases that reflect a subject's motivation, [19] for example, the desire for a positive self-image leading to egocentric bias and the avoidance of unpleasant cognitive dissonance. [20]
Examples of sampling bias include self-selection, pre-screening of trial participants, discounting trial subjects/tests that did not run to completion and migration bias by excluding subjects who have recently moved into or out of the study area, length-time bias, where slowly developing disease with better prognosis is detected, and lead time ...
After a hot December jobs report pared back investor's hopes for interest rate cuts in 2025, two key inflation readings will add to the discussion in the week ahead.
For more information, see Screening (medicine)#Length time bias. This long-standing model has a hidden assumption: namely, that all cancers inevitably progress. But some pre-clinical cancers will not progress to cause problems for patients. And if screening (or testing for some other reason) detects these cancers, overdiagnosis has occurred.