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Mirtazapine, sold under the brand name Remeron among others, is an atypical tetracyclic antidepressant, and as such is used primarily to treat depression. [11] [12] Its effects may take up to four weeks but can also manifest as early as one to two weeks. [12] [13] It is often used in cases of depression complicated by anxiety or insomnia.
Remeron (mirtazapine) – an atypical antidepressant, used off-label as a sleep aid; Restoril – a benzodiazepine used to treat insomnia; Risperdal (risperidone) – atypical antipsychotic used to treat schizophrenia, bipolar disorder and irritability associated with autism; Ritalin (methylphenidate) – a stimulant used to treat ADHD
Mirtazapine (Remeron) Setiptiline (Tecipul) Drugs that contain four rings not all fused together but are sometimes still classified as TeCAs include: Amoxapine (Asendin) – often classified as a TCA and grouped with the secondary amines; Quetiapine (Seroquel) - an atypical antipsychotic sometimes used as an adjunct antidepressant
amitriptyline – tricyclic antidepressant used to treat separation anxiety, excessive grooming dogs and cats; amlodipine – calcium channel blocker used to decrease blood pressure; amoxicillin – antibacterial; apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Quetiapine is currently the only antipsychotic to produce equal efficacy as a standalone therapy for mixed manic-depressive mood swings as it is when used in combination with an SSRI antidepressant. However, quetiapine is less potent than clozapine , amisulpride , olanzapine , risperidone , and paliperidone , respectively, in alleviating ...
Mirtazapine was developed by the same team of organic chemists and differs via addition of a nitrogen atom in one of the rings. [43] [44] (S)-(+)-Mianserin is approximately 200–300 times more active than its enantiomer (R)-(−)-mianserin; hence, the activity of mianserin lies in the (S)-(+) isomer. [citation needed]
Mirtazapine has also been used in the treatment of the motility disorder gastroparesis due to its anti-emetic effects. [27] Olanzapine , an atypical antipsychotic with anti-emetic properties similar to those of mirtazapine, also shows promise in treating chemotherapy-induced nausea and vomiting.
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