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Mitotic trigger waves are waves of Cyclin-dependent kinase 1 activity in cells that originate from pacemaker regions of the nucleus and propagate through the cytoplasm. [1]. Because trigger waves do not decrease in speed or amplitude during their propagation, they are more reliable at conveying molecular information across greater distances ...
The mitotic index is a measure of cellular proliferation. [1] It is defined as the percentage of cells undergoing mitosis in a given population of cells. Mitosis is the division of somatic cells into two daughter cells. Durations of the cell cycle and mitosis vary in different cell types. An elevated mitotic index indicates more cells are dividing.
W3Schools is a freemium educational website for learning coding online. [1] [2] Initially released in 1998, it derives its name from the World Wide Web but is not affiliated with the W3 Consortium. [3] [4] [unreliable source] W3Schools offers courses covering many aspects of web development. [5] W3Schools also publishes free HTML templates.
Cells in the mitotic phase are identified by the typical appearance of their chromosomes in the cell during the mitotic phase of the cell cycle. [4] Usually the number of mitotic figures is expressed as the total number in a defined number of high power fields, such as 10 mitoses in 10 high power fields.
In addition, when mitotic spindles are misaligned, MEN and subsequently Cdc14 are inhibited in a Bub2 and Bfa1-dependent manner to prevent degradation of mitotic cyclins and anaphase entry. [36] Sic1 is a nice example demonstrating how systems-level feedbacks interact to sense the environmental conditions and trigger cell cycle transitions.
SciPy (pronounced / ˈ s aɪ p aɪ / "sigh pie" [2]) is a free and open-source Python library used for scientific computing and technical computing. [3]SciPy contains modules for optimization, linear algebra, integration, interpolation, special functions, FFT, signal and image processing, ODE solvers and other tasks common in science and engineering.
Cell synchronization is a process by which cells in a culture at different stages of the cell cycle are brought to the same phase. Cell synchrony is a vital process in the study of cells progressing through the cell cycle as it allows population-wide data to be collected rather than relying solely on single-cell experiments.
The cyclins are necessary for the kinase subunit to function with the appropriate substrate. The mitotic cyclins can be grouped as cyclins A & B. These cyclins have a nine residue sequence in the N-terminal region called the “destruction box”, which can be recognized by the ubiquitin ligase enzyme which destroys the cyclins when appropriate.