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Miconazole inhibits the fungal enzyme 14α-sterol demethylase, resulting in a reduced production of ergosterol. [10] In addition to its antifungal actions, miconazole, similarly to ketoconazole , is known to act as an antagonist of the glucocorticoid receptor .
Clotrimazole, sold under the brand name Lotrimin, among others, is an antifungal medication. [2] It is used to treat vaginal yeast infections, oral thrush, diaper rash, tinea versicolor, and types of ringworm including athlete's foot and jock itch. [2]
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin [2] (a dermatomycosis), that may affect skin, hair, and nails. [1] Typically it results in a red, itchy, scaly, circular rash. [ 1 ]
Ringworm. What it looks like: Ringworm is a common skin infection caused by a fungus. It gets its name from its circular rash, which is often red, swollen, and cracked. Other symptoms to note ...
Cortizone-10 contains 1% hydrocortisone, which is the highest concentration allowed in over-the-counter products, according to the brand. The cream can alleviate itching for hours after ...
Ketoconazole is a racemic mixture consisting of cis-(2S,4R)-(−) and cis-(2R,4S)-(+) enantiomers. [10] The cis -(2 S ,4 R ) isomer was more potent in inhibiting progesterone 17α,20-lyase than its enantiomer ( IC 50 values of 0.05 and 2.38 μ M, respectively) and in inhibiting 11β-hydroxylase (IC 50 values of 0.152 and 0.608 μ M, respectively).
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