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Methemoglobinemia can be due to certain medications, chemicals, or food or it can be inherited. [2] Substances involved may include benzocaine , nitrites , or dapsone . [ 3 ] The underlying mechanism involves some of the iron in hemoglobin being converted from the ferrous [Fe 2+ ] to the ferric [Fe 3+ ] form. [ 3 ]
The main excretion pathway is through the urine where up to one-third of the administered compound was recovered unchanged. Major metabolites are 4-amino- m -cresol and to a lesser extent, N -acetyl-4-amino- m -cresol, [ 20 ] azoxytoluene, o -nitrosotoluene, N -acetyl- o -toluidine, N -acetyl- o -aminobenzyl alcohol, anthranilic acid, N -acetyl ...
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Many dog owners have already heard about the FDA warning and seen the articles on the terrible side effects experienced by some dogs that have been injected with the new arthritis drug Librela ...
It can even cause death! ... Related: First FDA-Approved Anti-Aging Medication for Dogs Might Be on Its Way. Many pet owners have found that their dogs have had severe reactions to the medication ...
In some cases, a drug can cause the immune system to mistakenly think the body's own red blood cells are dangerous, foreign substances. Antibodies then develop against the red blood cells. The antibodies attach to red blood cells and cause them to break down too early. It is known that more than 150 drugs can cause this type of hemolytic anemia ...
G6PD deficient red cells in combination with high levels of oxidants causes a cross-linking of sulfhydryl groups on globin chains which causes a denaturing and formation of Heinz body precipitates. [8] Heinz bodies can also be found in chronic liver disease. [9] Alpha-thalassemia. Normal adult hemoglobin is composed of two alpha and two beta ...
Most dogs, however, will need radiation, chemotherapy, and other medications. Even with those therapies, the survival time is short, so ivermectin could help if it proves to be useful.