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The suffix -pontin is derived from "pons," the Latin word for bridge, and signifies osteopontin's role as a linking protein. Osteopontin is an extracellular structural protein and therefore an organic component of bone. The gene has 7 exons, spans 5 kilobases in length and in humans it is located on the long arm of chromosome 4 region 22 ...
osteopontin (OPN) bone sialoprotein (BSP) dentin matrix protein 1 (DMP1) dentin sialophosphoprotein (DSPP) matrix extracellular phosphoglycoprotein (MEPE) The genes coding for members of the SIBLING protein family are similarly organized and are all located on human chromosome 4q21-23. [3]
OPN may stand for: . Osteopontin, a glycoprotein secreted by osteoblasts; Object Process Network, a simulation model meta-language; Optics & Photonics News, a magazine; Oneohtrix Point Never, recording alias of musician Daniel Lopatin
They synthesize dense, crosslinked collagen and specialized proteins in much smaller quantities, including osteocalcin and osteopontin, which compose the organic matrix of bone. In organized groups of disconnected cells, osteoblasts produce hydroxyapatite , the bone mineral , that is deposited in a highly regulated manner, into the inorganic ...
An osteocyte, an oblate shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. [1] The adult human body has about 42 billion of them. [2]
Osteonectin is a 40 kDa acidic and cysteine-rich glycoprotein consisting of a single polypeptide chain that can be broken into 4 domains: 1) a Ca 2+ binding domain near the glutamic acid-rich region at the amino terminus (domain I), 2) a cysteine-rich domain (II), 3) a hydrophilic region (domain III), and 4) an EF hand motif at the carboxy terminus region (domain IV).
15891 Ensembl ENSG00000029559 ENSMUSG00000029306 UniProt P21815 Q61711 RefSeq (mRNA) NM_004967 NM_008318 RefSeq (protein) NP_004958 NP_032344 Location (UCSC) Chr 4: 87.8 – 87.81 Mb Chr 5: 104.45 – 104.46 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Bone sialoprotein (BSP) is a component of mineralized tissues such as bone, dentin, cementum and calcified cartilage. BSP is a ...
The Enciclopedia Libre was founded by contributors to the Spanish Wikipedia who decided to start an independent project. Led by Edgar Enyedy, they left Wikipedia on 26 February 2002, and created the new website, provided by the University of Seville for free, with the freely licensed articles of the Spanish Wikipedia. [3]