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Zonisamide is an antiseizure drug chemically classified as a sulfonamide and unrelated to other antiseizure agents. The precise mechanism by which zonisamide exerts its antiseizure effect is unknown, although it is believed that the drug blocks sodium and T-type calcium channels , which leads to the suppression of neuronal hypersynchronization ...
Lacosamide has a K d value just under 5 μM and a B max of about 200 pM/mg. [34] The volume of distribution (V d) of lacosamide in plasma is 0.6 L/kg, which is close to the total volume of water. Lacosamide is ampiphilic and is thus hydrophilic while also lipophilic enough to cross the blood-brain barrier .
Tiagabine overdose can produce neurological symptoms such as lethargy, single or multiple seizures, status epilepticus, coma, confusion, agitation, tremors, dizziness, dystonias/abnormal posturing, and hallucinations, as well as respiratory depression, tachycardia, hypertension, and hypotension. [12]
One cup of low-fat milk has 8 grams of protein and 100 calories, while Greek yogurt provides 15 grams of protein in a small 5.3-ounce container. As for cottage cheese, half a cup has about 12 ...
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Video of the terrifying incident ran on the station’s morning news program, capturing the sound of at least eight gunshots, then screams, and briefly showed Flanagan, 41, holding a gun.
The pharmaceutical industry in Pakistan was estimated to be worth Rs. 748 billion (US$2.6 billion) in 2023, representing about 1% of the country's GDP. [1] The industry is largely import-dependent, with more than 90% of raw material being imported and only 12% of APIs locally produced. [1]