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Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval. The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents.
[1] Alatrofloxacin: 2006 Worldwide Serious hepatotoxicity leading to liver transplant or death. [2] Alclofenac: 1979 UK Vasculitis [3] Alpidem (Ananxyl) 1995 Worldwide Not approved in the US, withdrawn in France in 1994 [4] and the rest of the market in 1995 because of rare but serious hepatotoxicity. [3] [5] Alosetron (Lotronex) 2000 US
Bone marrow suppression, rhabdomyolysis, embryo-fetal toxicity, capillary leak syndrome, hepatotoxicity [20] 1.10 Platinum compounds: Carboplatin: IV: Reacts with DNA, inducing apoptosis, non-cell cycle specific. Ovarian cancer, lung cancer and squamous cell head and neck cancer
This is a list of drugs and substances that are known or suspected to cause Stevens–Johnson syndrome This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources .
Aprocitentan, sold under the brand name Tryvio, is a medication used to treat hypertension (high blood pressure). [1] It is developed by Idorsia. [4] It is taken by mouth. [1] Aprocitentan is a receptor antagonist that targets both endothelin A and endothelin B receptors. [5] [6] Aprocitentan was approved for medical use in the United States in ...
"Even a small amount can be fatal, as it can cause respiratory failure," he said. Carfentanil can sometimes be in the form of "pressed pills" that resemble prescription medications, the expert said.
Of these, amoxicillin-clavulanate is the most common cause of drug-induced liver injury, and paracetamol toxicity the most common cause of acute liver failure in the United States and Europe. [36] Herbal remedies and dietary supplements are another important cause of hepatitis; these are the most common causes of drug-induced hepatitis in Korea ...
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