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Midodrine, also known as 3,6-dimethoxy-β-hydroxy-N-aminoethanonyl-2-phenylethylamine, is a substituted phenethylamine derivative. [4] Midodrine is an odorless, white, crystalline powder, soluble in water and sparingly soluble in methanol. [19] Midodrine's experimental log P is -0.5 and its predicted log P ranges from -0.49 to -0.95.
Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels, [Note 1] and flow into the body's circulatory system, which distributes the drug to the body's organs and bodily systems. [Note 2]
[1] [2] [29] However, one study of 13 patients with hepatorenal syndrome showed significant improvement in kidney function when the two were used together (with midodrine given orally, octreotide given subcutaneously and both dosed according to blood pressure), with three patients surviving to discharge. [30]
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Each player is given 2 sore loser coins upon the start of the game, and the remainder are placed in the centre of the board. A player collects a sore loser coin from the Bank if they have to do any of the following: pay rent to another player, pay taxes and bills to the Bank, go to jail, land on a property that they own, or draw a Chance or ...
K: Cone for rectal insertion. Before the Columbian Exchange, tobacco was unknown in the Old World. The Native Americans, from whom the first Western explorers learnt about tobacco, used the leaf for a variety of purposes, including religious worship, but Europeans soon became aware that the Americans also used tobacco for medicinal purposes.
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A variation of hair twists is called a "twist out", [5] where twisted hair is untwisted to create a large, loosely crimped texture. There are two different variations to a "twist out," one method can be done with using two stands of hair and another method uses three stands of hair called a "three stand twist out".