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Newer agents such as the melatonin receptor agonists may be more suitable and effective for the management of chronic insomnia in elderly people. Long-term use of sedative-hypnotics for insomnia lacks an evidence base and is discouraged for reasons that include concerns about such potential adverse drug effects as cognitive impairment ...
In addition, the effectiveness and safety of long-term use of these agents remain to be determined. It was concluded that more research is needed to evaluate the long-term effects of treatment and the most appropriate management strategy for elderly persons with chronic insomnia. [18] A 2009 meta-analysis found a higher rate of infections. [19]
A meta-analysis of randomized, controlled clinical trials which compared benzodiazepines against zaleplon or other Z-drugs such as zolpidem, zopiclone, and eszopiclone has found few clear and consistent differences between zaleplon and the benzodiazepines in terms of sleep onset latency, total sleep duration, number of awakenings, quality of ...
This has led to the Z-drugs becoming widely prescribed for the treatment of insomnia particularly in elderly patients. [12] [13] [14] Almost a third of all prescriptions written for Z-drugs are for adults over the age of 65. [15] Long-term use is not recommended as tolerance and addiction can occur. [16]
Markeem Benson is accused of murdering Renise Wolfe in Nevada
Eurodin, Prosom – a benzodiazepine derivative with anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties, commonly prescribed for short-term treatment of insomnia F [ edit ]
A coroner has issued a warning about the effects of medication used to treat depression after the husband of Prince and Princess Michael of Kent’s daughter took his own life.
In fact, long-term use of Ozempic may reduce the risk of major adverse cardiovascular events like heart attack in people with type 2 diabetes. stefanamer / iStock. 6. Thyroid Cancer.