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Oral ketoconazole is indicated for use in these countries when the indication is a severe or life-threatening systemic infection and alternatives are unavailable. [18] However, topical ketoconazole, which does not distribute systemically, is safe and widely used still. [18]
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Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals, environmental change and host factors. [1] Like resistance to antibacterials, antifungal resistance can be driven by antifungal use in agriculture.
Zinc pyrithione is approved for over-the-counter topical use in the United States as a treatment for dandruff and is the active ingredient in several anti-dandruff shampoos and body wash gels. In its industrial forms and strengths, it may be harmful by contact or ingestion.
In 72% of the cases, benzodiazepines were the only drug consumed. Thus, many of deaths associated with benzodiazepine overdoses may not be a direct result of the toxic effects but either due to being combined with other drugs or used as a tool to kill oneself using a different method, e.g. drowning. [55]
Swallow each tablet whole, using only a small sip of water (four ounces or less). Wait 30 minutes before having additional liquids, food, or other oral medications.
Newts begin their lives as aquatic larvae similar to tadpoles, though elongated and with external gills. Once newt larvae mature into their adult form, which takes about four to six months, they will leave the water and live underground [7] until they are ready to breed, which is typically in four to six years. [8]
Never use repellents over cuts, wounds, or irritated skin. When using sprays, do not spray directly into face; spray on hands first and then apply to face. Do not apply near eyes and mouth, and ...
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