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Clobetasol is believed to work by activating steroid receptors. [8] Clobetasol propionate was patented in 1968 and came into medical use in 1978. [13] It is available as a generic medication. [10] In 2022, it was the 156th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [14] [15]
Clobetasol propionate 0.05%; Diflucortolone valerate 0.3% (not available in the US) Fluocinonide 0.1%; Flurandrenolide 4 mcg/cm 2; Halobetasol propionate 0.05%;
Clobetasol propionate 0.05% (Dermovate) Betamethasone dipropionate 0.25% (Diprolene) ... (Capex shampoo, Dermasmooth) Desonide 0.05% (DesOwen cream, lotion) Class VII
Clobetasol is a synthetic glucocorticoid corticosteroid. A propionate ester of clobetasol, clobetasol propionate , has also been marketed, and is far more widely used in comparison. [ 2 ] [ 3 ]
In dermatology, topical clobetasone butyrate helps to reduce the itchiness and erythema associated with eczema and dermatitis. [5]In ophthalmology, clobetasone butyrate 0.1% eye drops have been shown to be safe and effective in the treatment of dry eyes in Sjögren syndrome.
Topical and intralesional corticosteroids, such as clobetasol propionate, have also shown to be an effective treatment for AT and AU patients. [7] [8] A controlled study comprising 28 patients found positive terminal hair growth in eight of the patients (28.5%) using a 0.05% clobetasol propionate ointment. [12]
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