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Folinic acid, also known as leucovorin, is a medication used to decrease the toxic effects of methotrexate and pyrimethamine. [2] [3] It is also used in combination with 5-fluorouracil to treat colorectal cancer and pancreatic cancer, may be used to treat folate deficiency that results in anemia, and methanol poisoning.
They are given by injection. [2] Common side effects may include joint pain, rash, vomiting, and headache. [4] Serious side effects may include heart attacks, stroke, increased cancer growth, or pure red cell aplasia. [2] It is unclear if use is safe during pregnancy. [5] [6] They work similar to naturally occurring erythropoietin. [1]
Both high-folate diets and supplemental folic acid may help reduce the toxic side-effects of low-dose methotrexate without decreasing its effectiveness. [ 8 ] [ 9 ] Anyone taking low-dose methotrexate for the health problems listed above should consult with a physician about the need for a folic acid supplement.
The best vitamins, minerals and nutrients for hair growth include vitamin A, vitamin B12, folic acid, vitamin C, vitamin D, vitamin E, biotin, zinc, iron, protein, keratin and omega-3 fatty acids.
The drug has been shown to slow hair loss and promote partial hair regrowth in about two-thirds of men. ... Our biotin gummies contain folic acid, plus vitamins B7, B12, C, D and E ...
They are taken by mouth, injection into a vein, or injection into a muscle. [12] While benefits may be seen in days, up to two months may be required until iron levels return to normal. [14] Common side effects include constipation, abdominal pain, dark stools, and diarrhea. [14]
The 2013–2014 survey reported that for adults ages 20 years and older, men consumed an average of 249 μg/day folate from food plus 207 μg/day of folic acid from consumption of fortified foods, for a combined total of 601 μg/day of dietary folate equivalents (DFEs because each microgram of folic acid counts as 1.7 μg of food folate).
The U.S. Preventive Services Task Force released a draft recommendation advising against using vitamin D to prevent falls and fractures in people over 60. Pharmacist Katy Dubinsky weighs in.