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Thick smears allow the microscopist to screen a larger volume of blood and are about eleven times more sensitive than the thin film, so picking up low levels of infection is easier on the thick film, but the appearance of the parasite is much more distorted and therefore distinguishing between the different species can be much more difficult.
This is a trashy smear, but it does show an extremely advanced case of the microcytic/hypochromic anemia characteristic of iron deficiency. The mean corpuscular volume (MCV) was 55 fL (reference range: 80 - 94 fL). Pathological and histological images courtesy of Ed Uthman at flickr. Date: 8 March 2010, 16:35: Source
A blood smear showing hypochromic (and microcytic) anemia. Note the increased central pallor of the red blood cells. Hypochromic anemia is a generic term for any type of anemia in which the red blood cells are paler than normal. (Hypo- refers to less, and chromic means colour.) A normal red blood cell has a biconcave disk shape and will have an ...
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Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). [2]
A human peripheral blood smear; NRBCs are visible as larger cells with dark centers.. A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus.
[15] [53] With more severe iron-deficiency anemia, the peripheral blood smear may show hypochromic, pencil-shaped cells and, occasionally, small numbers of nucleated red blood cells. [57] The platelet count may be slightly above the high limit of normal in iron-deficiency anemia (termed a mild thrombocytosis ), but severe cases can present with ...