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  2. Treatment and control groups - Wikipedia

    en.wikipedia.org/wiki/Treatment_and_control_groups

    A clinical control group can be a placebo arm or it can involve an old method used to address a clinical outcome when testing a new idea. For example in a study released by the British Medical Journal, in 1995 studying the effects of strict blood pressure control versus more relaxed blood pressure control in diabetic patients, the clinical control group was the diabetic patients that did not ...

  3. Research design - Wikipedia

    en.wikipedia.org/wiki/Research_design

    A research design typically outlines the theories and models underlying a project; the research question(s) of a project; a strategy for gathering data and information; and a strategy for producing answers from the data. [1] A strong research design yields valid answers to research questions while weak designs yield unreliable, imprecise or ...

  4. Glossary of experimental design - Wikipedia

    en.wikipedia.org/.../Glossary_of_experimental_design

    Balanced design: An experimental design where all cells (i.e. treatment combinations) have the same number of observations. Blocking : A schedule for conducting treatment combinations in an experimental study such that any effects on the experimental results due to a known change in raw materials, operators, machines, etc., become concentrated ...

  5. Phases of clinical research - Wikipedia

    en.wikipedia.org/wiki/Phases_of_clinical_research

    The design of individual trials may be altered during a trial – usually during Phase II or III – to accommodate interim results for the benefit of the treatment, adjust statistical analysis, or to reach early termination of an unsuccessful design, a process called an "adaptive design".

  6. Matching (statistics) - Wikipedia

    en.wikipedia.org/wiki/Matching_(statistics)

    Matching is a statistical technique that evaluates the effect of a treatment by comparing the treated and the non-treated units in an observational study or quasi-experiment (i.e. when the treatment is not randomly assigned).

  7. Multimethodology - Wikipedia

    en.wikipedia.org/wiki/Multimethodology

    Multimethodology or multimethod research includes the use of more than one method of data collection or research in a research study or set of related studies.Mixed methods research is more specific in that it includes the mixing of qualitative and quantitative data, methods, methodologies, and/or paradigms in a research study or set of related studies.

  8. Intention-to-treat analysis - Wikipedia

    en.wikipedia.org/wiki/Intention-to-treat_analysis

    ITT analysis is intended to avoid various misleading artifacts that can arise in intervention research such as non-random attrition of participants from the study or crossover. ITT is also simpler than other forms of study design and analysis, because it does not require observation of compliance status for units assigned to different ...

  9. Randomized controlled trial - Wikipedia

    en.wikipedia.org/wiki/Randomized_controlled_trial

    Peer review of results is an important part of the scientific method. Reviewers examine the study results for potential problems with design that could lead to unreliable results (for example by creating a systematic bias ), evaluate the study in the context of related studies and other evidence, and evaluate whether the study can be reasonably ...

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