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  2. Tizanidine - Wikipedia

    en.wikipedia.org/wiki/Tizanidine

    Tizanidine is a derivative of 2,1,3-benzothiadiazole and its first published synthesis was reported in a patent. [17] The 5-chloro-2,1,3-benzothiadiazol-4-amine intermediate was a known compound, produced in three steps from 4-chlorophenylenediamine as shown. [ 18 ]

  3. Chlorzoxazone - Wikipedia

    en.wikipedia.org/wiki/Chlorzoxazone

    [medical citation needed] Elucidation of the exact mechanism of action is ongoing but there is limited study due to the existence of more effective, safe muscle relaxants (e.g., diazepam, cyclobenzaprine, tizanidine), greatly limiting the potential benefit of identifying novel compounds which share chlorzoxazone's mechanism of action.

  4. Alpha-2 adrenergic receptor - Wikipedia

    en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor

    Norepinephrine has higher affinity for the α 2 receptor than epinephrine does, and therefore relates less to the latter's functions. [16] Nonselective α 2 agonists include the antihypertensive drug clonidine, [16] which can be used to lower blood pressure and to reduce hot flashes associated with menopause.

  5. Nonsteroidal anti-inflammatory drug - Wikipedia

    en.wikipedia.org/wiki/Nonsteroidal_anti...

    NSAID identification on label of generic ibuprofen, an over-the-counter non-steroidal anti-inflammatory drug. Non-steroidal anti-inflammatory drugs [1] [3] (NSAID) [1] are members of a therapeutic drug class which reduces pain, [4] decreases inflammation, decreases fever, [1] and prevents blood clots.

  6. Ibuprofen - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen

    Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names including Advil, Motrin, and Nurofen.

  7. Antispasmodic - Wikipedia

    en.wikipedia.org/wiki/Antispasmodic

    Another class of antispasmodics for such treatment includes cyclobenzaprine, carisoprodol, diazepam, orphenadrine, and tizanidine. [7] Meprobamate is another effective antispasmodic which was first introduced for clinical usage in 1955 mainly as an anxiolytic and soon afterward became a blockbuster psychotropic drug.

  8. Talk:Tizanidine - Wikipedia

    en.wikipedia.org/wiki/Talk:Tizanidine

    It does not distinguish poly-drug combinations, especially with illegal drugs, nor cases of intentional drug overdose. Number of deaths where the person had tizanidine in their system does not equate to abuse potential.

  9. Ibuprofen/paracetamol - Wikipedia

    en.wikipedia.org/wiki/Ibuprofen/paracetamol

    Ibuprofen/paracetamol, sold under the brand name Combogesic among others, is a fixed-dose combination of two medications, ibuprofen, a non-steroidal anti-inflammatory drug (NSAID); and paracetamol (acetaminophen), an analgesic and antipyretic. [6] It is available as a generic medication. [9] [10] [11]

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