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Prognosis (Greek: πρόγνωσις "fore-knowing, foreseeing"; pl.: prognoses) is a medical term for predicting the likelihood or expected development of a disease, including whether the signs and symptoms will improve or worsen (and how quickly) or remain stable over time; expectations of quality of life, such as the ability to carry out daily activities; the potential for complications and ...
As a system approaches failure, the time window to take a corrective action gets shorter and consequently the accuracy of predictions becomes more critical for decision making. Finally, randomness and noise in the process, measurements, and prediction models are unavoidable and hence prognostics inevitably involves uncertainty in its estimates.
In a prediction rule study, investigators identify a consecutive group of patients who are suspected of having a specific disease or outcome. The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient.
The first clinical prediction model reporting guidelines were published in 2015 (Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD)), and have since been updated. [10] Predictive modelling has been used to estimate surgery duration.
Real prognostic variables are usually known with some uncertainty, may be difficult to measure, and their correlation to the system's state of health may not be exact. Examples of prognostic variables are the age of a vehicle and its odometer reading: the older a car is, and the longer it has been driven, the more worn it can be expected to be ...
Five-year survival rates can be used to compare the effectiveness of treatments. Use of five-year survival statistics is more useful in aggressive diseases that have a shorter life expectancy following diagnosis, such as lung cancer, and less useful in cases with a long life expectancy, such as prostate cancer.
Predictive genomics is at the intersection of multiple disciplines: predictive medicine, personal genomics and translational bioinformatics.Specifically, predictive genomics deals with the future phenotypic outcomes via prediction in areas such as complex multifactorial diseases in humans. [1]
In a non-statistical sense, the term "prediction" is often used to refer to an informed guess or opinion.. A prediction of this kind might be informed by a predicting person's abductive reasoning, inductive reasoning, deductive reasoning, and experience; and may be useful—if the predicting person is a knowledgeable person in the field.