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Many women with Hashimoto's disease develop an underactive thyroid. They may have mild or no symptoms at first, but symptoms tend to worsen over time. If a woman is pregnant and has symptoms of Hashimoto's disease, the clinician will do an exam and order one or more tests. [1] [2] [3] The thyroid is a small gland in the front of the neck.
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
[8] [60] [59] [61] Nonetheless, high maternal FT4 levels during pregnancy have been associated with impaired brain developmental outcomes of the offspring and this was independent of hCG levels. [62] Propylthiouracil is the preferred antithyroid medication in the 1st trimester of pregnancy as it is less teratogenic than methimazole. [8]
Patients with Graves' disease can also undergo periods of hypothyroidism (inadequate production of thyroid hormone; see symptoms of hypothyroidism), due to the challenges of finding the right dosage of thyroid hormone suppression and/or supplementation. The body's need for thyroid hormone can also change over time, such as in the first months ...
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Universal screening for thyroid diseases during pregnancy is controversial, however, one study "supports the potential benefit of universal screening". [133] Pregnant women may have anti-thyroid antibodies (5%–14% of pregnancies [15]), poor thyroid function resulting in hypothyroidism, or both. Each is associated with risks.
Several mysterious symptoms—from weight changes to irritability to fatigue—can indicate the need to have your thyroid checked. Your thyroid gland controls your body’s metabolism and is one ...
Questions remain over how appropriately it is prescribed, however, as side effects can cause problems. ... Low levels of thyroid hormones can lead to symptoms including fatigue, weight gain, cold ...
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