Search results
Results from the WOW.Com Content Network
The plaque reduction neutralization test is used to quantify the titer of neutralizing antibody for a virus. [1] [2] The serum sample or solution of antibody to be tested is diluted and mixed with a viral suspension. This is incubated to allow the antibody to react with the virus. This is poured over a confluent monolayer of host cells.
However, serum therapy is today still used as the first line of defence during an outbreak as it can relatively quickly obtained. [19] [20] Serum therapy was shown to reduce mortality in patients during the 2009 swine flu pandemic [21] and the Western African Ebola virus epidemic. [22] It is also being tested as possible treatment for COVID-19.
This technique makes many copies of the virus genome using virus-specific probes. Variations of PCR such as nested reverse transcriptase PCR and real time PCR can also be used to determine viral loads in patient serum. This is often used to monitor treatment success in HIV cases.
Reporter virus particles (RVPs) are replication-incompetent virus particles engineered to express one or more reporter genes upon infecting susceptible cells. [ 1 ] [ 2 ] [ 3 ] Since the RVP genome lacks genes essential for viral replication, RVPs are capable of only a single round of infection.
Also sometimes called the Norwalk virus or winter vomiting bug, norovirus is an extremely contagious virus. It is a common cause of illness outbreaks on cruise ships, where more than 90% of ...
The complement fixation test is an immunological medical test that can be used to detect the presence of either specific antibody or specific antigen in a patient's serum, based on whether complement fixation occurs. It was widely used to diagnose infections, particularly with microbes that are not easily detected by culture methods, and in ...
In today's puzzle, there are seven theme words to find (including the spangram). Hint: The first one can be found in the top-half of the board. Here are the first two letters for each word: DR. IN ...
A 2010 review study by Puren et al. [2] categorizes viral load testing into three types: (1) nucleic acid amplification based tests (NATs or NAATs) commercially available in the United States with Food and Drug Administration (FDA) approval, or on the market in the European Economic Area (EEA) with the CE marking; (2) "Home–brew" or in-house NATs; (3) non-nucleic acid-based test.