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Video of relevant anatomy Coronal slices of human brain showing the basal ganglia. White matter is shown in dark gray, gray matter is shown in light gray. Anterior: striatum, globus pallidus (GPe and GPi) Posterior: subthalamic nucleus (STN), substantia nigra (SN) The basal ganglia form a fundamental component of the cerebrum.
The subthalamic nucleus (STN) is a small lens-shaped nucleus in the brain where it is, from a functional point of view, part of the basal ganglia system. In terms of anatomy, it is the major part of the subthalamus. As suggested by its name, the subthalamic nucleus is located ventral to the thalamus.
The pallidothalamic tracts (or pallidothalamic connections) [1] are a part of the basal ganglia. They provide connectivity between the internal globus pallidus (GPi) and the thalamus , primarily the ventral anterior nucleus and the ventral lateral nucleus .
The basal ganglia are located bilaterally, and have rostral and caudal divisions. The putamen is located in the rostral division as part of the striatum. The basal ganglia receive input from the cerebral cortex, via the striatum. This is a transverse section of the striatum from a structural MR image.
The globus pallidus is a structure in the brain involved in the regulation of voluntary movement. [8] It is part of the basal ganglia, which, among many other functions, regulate movements that occur on the subconscious level. The globus pallidus has a predominantly inhibitory effect on movement regulation, balancing cerebellar excitation.
The substantia nigra (SN) is a basal ganglia structure located in the midbrain that plays an important role in reward and movement. Substantia nigra is Latin for "black substance", reflecting the fact that parts of the substantia nigra appear darker than neighboring areas due to high levels of neuromelanin in dopaminergic neurons. [1]
The cerebrum (pl.: cerebra), telencephalon or endbrain [1] is the largest part of the brain, containing the cerebral cortex (of the two cerebral hemispheres) as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In the human brain, the cerebrum is the uppermost region of the central nervous system.
The ventral pallidum (VP) is a structure within the basal ganglia of the brain.It is an output nucleus whose fibres project to thalamic nuclei, such as the ventral anterior nucleus, the ventral lateral nucleus, and the medial dorsal nucleus.