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The longest-lived of these isotopes, and the most relevantly studied, are 90 Sr with a half-life of 28.9 years, 85 Sr with a half-life of 64.853 days, and 89 Sr (89 Sr) with a half-life of 50.57 days. All other strontium isotopes have half-lives shorter than 50 days, most under 100 minutes.
The decay of Rubidium-82, which undergoes positron emission.. Rubidium-82 is produced by electron capture of its parent nucleus, strontium-82.The generator contains accelerator produced 82 Sr adsorbed on stannic oxide in a lead-shielded column and provides a means for obtaining sterile nonpyrogenic solutions of rubidium chloride (halide salt form capable of injection).
While natural strontium (which is mostly the isotope strontium-88) is stable, the synthetic strontium-90 is radioactive and is one of the most dangerous components of nuclear fallout, as strontium is absorbed by the body in a similar manner to calcium. Natural stable strontium, on the other hand, is not hazardous to health.
Radium-223 chloride, strontium-89 chloride and samarium-153 EDTMP are used to treat secondary cancer in the bones. [ 9 ] [ 10 ] Radium and strontium mimic calcium in the body. [ 11 ] Samarium is bound to tetraphosphate EDTMP , phosphates are taken up by osteoblastic (bone forming) repairs that occur adjacent to some metastatic lesions.
A medical isotope is an isotope used in medicine. The first uses of isotopes in medicine were in radiopharmaceuticals , and this is still the most common use. However more recently, separated stable isotopes have come into use.
Positron emission tomography (PET) [1] is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.
Pecher filed a patent in May 1941 for the synthesis of strontium-89 and yttrium-86 using cyclotrons and described the use of strontium for therapeutic uses . [24] The groundbreaking work of Pecher was forgotten for decades due to the classification of information linked to the Manhattan project and the American nuclear weapons program.
Strontium belongs to the same periodic family as calcium (alkaline earth metals), and is metabolised in a similar fashion, preferentially targeting metabolically active regions of the bone. 89 Sr is an artificial radioisotope used in the treatment of osseous (bony) metastases of bone cancer .