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According to a study in JAMA Dermatology, the prescribing rates of spironolactone for acne in women rose about 300% from 2017 to 2020. According to a study in JAMA Dermatology, the prescribing ...
Side effects of spironolactone in clinical studies for acne in women Side effect RCTs Tooltip Randomized controlled trials (n (ITT Tooltip Intention-to-treat analysis) = 326) Case series (n (ITT Tooltip Intention-to-treat analysis) = 663) Number % Number % Menstrual irregularities: 38: 13.4 (of 283) 216: 33.4 (of 646) Breast tenderness: 8: 2.5: ...
[145] [146] [147] However, a 2017 hybrid systematic review found that the incidence of depression in women treated with spironolactone for acne was less than 1%. [63] Likewise, a 10-year observational study found that the incidence of depression in 196 transgender women taking high-dose spironolactone in combination with an estrogen was less ...
4. See if a vitamin or supplement might help. If you're not comfortable trying a prescription medication, there are some vitamins and supplements that could potentially help treat hormonal acne ...
Spironolactone blocks your sensitive receptors from your androgens (aka the "male" sex hormones), which helps reduce oil and acne. It's a once-a-day treatment that's typically super effective ...
A 1991 review reported that the influences of spironolactone on androgen levels in women were variable and inconsistent. [ 78 ] Spironolactone has shown no significant effect on levels of testosterone, estradiol, luteinizing hormone, and follicle-stimulating hormone in men.
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