Ad
related to: glipizide mode of actiongoodrx.com has been visited by 100K+ users in the past month
Search results
Results from the WOW.Com Content Network
Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. [ 1 ] [ 2 ] It is used together with a diabetic diet and exercise.
Mechanism of action [7] Advantages [55] Disadvantages [55] Sulfonylureas (glyburide, glimepiride, glipizide) Stimulating insulin release by pancreatic beta cells by inhibiting the K ATP channel: Inexpensive; Fast onset of action; No effect on blood pressure; No detrimental effect on low-density lipoprotein; Lower risk of gastrointestinal side ...
Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. [1] [2] It is regarded as a second-line option compared to metformin, due to metformin's well-established safety and efficacy. [1]
They include glibenclamide (glyburide), glibornuride, gliclazide, glipizide, gliquidone, glisoxepide and glyclopyramide. Third-generation drugs: They include glimepiride , although it is sometimes considered a second-generation drug.
The mechanism of DPP-4 inhibitors is to increase incretin levels (GLP-1 and GIP), [2] [3] [4] which inhibit glucagon release, which in turn increases insulin secretion, decreases gastric emptying, and decreases blood glucose levels.
The mechanism of action on a cellular level is not well understood. Work is underway to define this mechanism as a prodiuretic with great promise. However, it has been shown that binding of different sugars to the glucose site affects the orientation of the aglycone in the access vestibule. So when the aglycone binds it affects the entire ...
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Hyperglycemic action may be caused by danazol, chlorpromazine, glucocorticoids, progestogens, or β-2 agonists. Its hypoglycemic action may be potentiated by phenylbutazone, alcohol, fluconazole, β-blockers, and possibly ACE inhibitors. It has been found that rifampin increases gliclazide metabolism in humans in vivo. [15]
Ad
related to: glipizide mode of actiongoodrx.com has been visited by 100K+ users in the past month