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In urine cytology, collected urine is examined microscopically. One limitation, however, is the inability to definitively identify low-grade cancer cells and urine cytology is used mostly to identify high-grade tumors. [4] If the test detects atypical or cancerous cells, further tests may be recommended, such as cystoscopy and a CT scan.
The interpretation of urinalysis takes into account the results of physical, chemical and microscopic examination and the person's overall condition. Urine test results should always be interpreted using the reference range provided by the laboratory that performed the test, or using information provided by the test strip/device manufacturer. [136]
Reference ranges for urine tests are described below: Measurement Lower limit Upper limit Unit Urinary specific gravity: 1.003 [1] [2] 1.030 [1] [2] g/mL Urobilinogen:
Urine cytology — cytopathological examination of cells in the urine, used to screen for cancer [21] Urine protein electrophoresis — classification and measurement of different proteins in the urine; used to help diagnose monoclonal gammopathies [22] Urine organic acids, urine amino acids — used to test for some inborn errors of metabolism [8]
The pH of urine normally vary between 4.5 and 8 with the first urine produced in the morning generally being more acidic and the urine produced after meals generally more alkaline. [4] Normal reference values are not provided for urine pH as the variation is too wide and results have to be considered in the context of the other quantifiable ...
The most common type of cast, hyaline casts are solidified Tamm–Horsfall mucoprotein secreted from the tubular epithelial cells of individual nephrons. Low urine flow, concentrated urine, or an acidic environment can contribute to the formation of hyaline casts, and as such, they may be seen in normal individuals in dehydration or vigorous exercise.
Severe bladder tumors often shed cells into the urine; these can be detected by urine cytology, where cells are collected from a urine sample, and viewed under a microscope. [6] [7] Cytology can detect around two thirds of high-grade tumors, but detects just 1 in 8 low-grade tumors. [8]
Myoglobinuria is the presence of myoglobin in the urine, which usually results from rhabdomyolysis or muscle injury. [1] Myoglobin is present in muscle cells as a reserve of oxygen . Signs and symptoms