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These investigations show that the M. globosa is the species that causes most skin disease in humans, and that it is the most common cause of dandruff and seborrhoeic dermatitis (though M. restricta is also involved). [6] There can be as many as ten million M. globosa organisms on a human head. [4]
As the fungus requires fat to grow, [3] it is most common in areas with many sebaceous glands: on the scalp, [4] face, and upper part of the body. When the fungus grows too rapidly, the natural renewal of cells is disturbed, and dandruff appears with itching (a similar process may also occur with other fungi or bacteria).
The majority of tinea versicolor is caused by the fungus Malassezia globosa, although Malassezia furfur is responsible for a small number of cases. [ 2 ] [ 3 ] These yeasts are normally found on the human skin and become troublesome only under certain conditions, such as a warm and humid environment, although the exact conditions that cause ...
“The fungus feeds off the skin’s sebum and excretes end products onto the scalp which can irritate the scalp skin, resulting in dandruff and its symptoms like dryness, itch, and flaking ...
Malassezia furfur is a fungus that lives on the superficial layers of the dermis.It generally exists as a commensal organism forming a natural part of the human skin microbiota, but it can gain pathogenic capabilities when morphing from a yeast to a hyphal form during its life cycle, through unknown molecular changes. [2]
Malassezia folliculitis or pityrosporum folliculitis, [1] is a skin condition caused by infection by Malassezia (formerly Pityrosporum) yeast. [2]: 314 The skin of the upper trunk area including the back, chest, arms and sometimes the neck is often affected and this condition is often seen in young to middle aged adults, although it has been known to occur in adults well into their sixties ...
Malassezia yeast is believed to play a role. [6] It is not a result of poor hygiene. [7] Diagnosis is typically clinical and based on the symptoms present. [4] [8] The condition is not contagious. [9] The typical treatment is topical antifungal cream and anti-inflammatory agents. [3] Specifically, ketoconazole or ciclopirox are effective. [10]
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. [2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. [2]