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Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [23] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction , thus causing flaccid paralysis . [ 24 ]
To calculate the cost basis for real estate, first add up these costs: The original purchase price of the property. Closing costs. Major home improvements. Costs to repair damage to the home and ...
Average wholesale price. In the United States, the average wholesale price ( AWP) is a prescription drug term referring to the average price for medications offered at the wholesale level. [ 1] The metric was originally intended to convey real pricing information to third-party payers, including government prescription drug programs.
Basis of estimate ( BOE) is a tool used in the field of project management by which members of the project team, usually estimators, project managers, or cost analysts, calculate the total cost of the project. Through carefully planned equations, hierarchical listing of elements, standard calculations, checklists of project elements and other ...
Sources say the pharmaceutical company that manufactures Botox, Allergan, charges providers around $6-7 per unit, making the average patient cost more like $10-15 per unit (with metropolitan areas ...
Equivalent annual cost. In finance, the equivalent annual cost ( EAC) is the cost per year of owning and operating an asset over its entire lifespan. It is calculated by dividing the negative NPV of a project by the "present value of annuity factor": , where. where r is the annual interest rate and. t is the number of years.
Calculation of Point of Total assumption (the case when EAC exceeds PTA that should be treated as a risk trigger, is shown) The point of total assumption (PTA) is a point on the cost line of the profit-cost curve determined by the contract elements associated with a fixed price plus incentive-Firm Target (FPI) contract above which the seller effectively bears all the costs of a cost overrun.
The wholesale price index (WPI) is based on the wholesale price of a few relevant commodities of over 240 commodities available. The commodities chosen for the calculation are based on their importance in the region and the point of time the WPI is employed. For example, in India about 435 items were used for calculating the WPI in base year ...