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Thrombus. A thrombus (pl. thrombi), colloquially called a blood clot, is the final product of the blood coagulation step in hemostasis. There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor.
Thrombosis (from Ancient Greek θρόμβωσις (thrómbōsis) 'clotting') is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system. When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a blood clot to prevent blood loss.
Left ventricular thrombus is a blood clot (thrombus) in the left ventricle of the heart. LVT is a common complication of acute myocardial infarction (AMI). [1][2] Typically the clot is a mural thrombus, meaning it is on the wall of the ventricle. [3] The primary risk of LVT is the occurrence of cardiac embolism, [1][4] in which the thrombus ...
Thromboembolism. Animation showing the formation of an occlusive blood clot in a vein. Several platelets attach to the lips of the valve, narrowing the opening and causing more platelets and red blood cells to pool and clot. Clotting of immobile blood on both sides of the blockage can cause the clot to spread in both directions.
A thrombus, or a blood clot, is a mobilized mass of blood cells that circulates within the body. [21] [22] Thrombi can occlude veins (venous thrombosis) or arteries (arterial thrombosis). The etiology of thrombosis is described by Virchow's Triad, which includes hemostasis, vascular wall damage, and hypercoagulability. [21]
Thrombopoiesis is the formation of thrombocytes (blood platelets) in the bone marrow. Thrombopoietin is the main regulator of thrombopoiesis. Thrombopoietin affects most aspects of the production of platelets. This includes self-renewal and expansion of hematopoietic stem cells, stimulating the increase of megakaryocyte progenitor cells, and ...
Coronary thrombosis is defined as the formation of a blood clot inside a blood vessel of the heart. This blood clot may then restrict blood flow within the heart, leading to heart tissue damage, or a myocardial infarction, also known as a heart attack. [1] Coronary thrombosis is most commonly caused as a downstream effect of atherosclerosis, a ...
H&E stain. Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platelets, forms a hemostatic plug or clot over a wound site. When the lining of a blood vessel is ...