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A positive rheumatoid factor test means that the level of rheumatoid factor in the patient’s blood is considered to be high. Rheumatoid factor was first described in connection to rheumatoid arthritis in 1940. For decades, a positive rheumatoid arthritis test was used to diagnose those with symptoms of rheumatoid arthritis.
A rheumatoid factor test measures the amount of rheumatoid factor in your blood. Rheumatoid factors are proteins made by your immune system that can attack healthy tissue in the body. High levels of rheumatoid factor in the blood are most often related to autoimmune diseases, such as rheumatoid arthritis and Sjogren syndrome.
A rheumatoid factor level over 100 is strongly associated with autoimmune conditions such as RA. However, a high rheumatoid factor level can also indicate cancer, chronic infections,...
A normal, healthy amount of rheumatoid factor is less than 20 units per milliliter (<20 U/mL). Your provider might also refer to your test as being negative or positive. A negative result means you have a normal amount of RF in your blood.
Rheumatoid factor (RF) levels above a normal range can indicate autoimmune conditions, such as rheumatoid arthritis (RA).
Rheumatoid factor (RF) is an antibody in the blood often present in rheumatoid arthritis and some other autoimmune diseases, aiding in diagnosis.
Rheumatoid factor is a blood test that helps to diagnose rheumatoid arthritis, lupus, and sarcoidosis. Elevated test results, or high levels, indicate severe disease. Learn about the normal range for rheumatoid factor.
The normal range of RF is from 0-20 IU/ml. RF above 20 IU/ml is not considered enough to diagnose RA, as there other reasons the RF level may be elevated. Some conditions and medical procedures that can raise RF levels include: other autoimmune diseases, certain chronic infections, diabetes, bacterial endocarditis, cancer, normal aging ...
Rheumatoid factors are antibodies with various isotypes and affinities, directed against the Fc portion of immunoglobulin G. The commonly mentioned rheumatoid factor is an IgM RF, although other immunoglobulin types, including IgG and IgA, are rarely found.
Usually, a rheumatoid factor that high is associated with either rheumatoid arthritis or Sjogren’s syndrome. However, a lab test by itself does not make a diagnosis. It has to be considered along with the individual patient’s signs and symptoms.