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  2. P-glycoprotein - Wikipedia

    en.wikipedia.org/wiki/P-glycoprotein

    P-gp is a 170 kDa transmembrane glycoprotein, which includes 10–15 kDa of N-terminal glycosylation.The N-terminal half of the protein contains six transmembrane helixes, followed by a large cytoplasmic domain with an ATP-binding site, and then a second section with six transmembrane helixes and an ATP-binding domain that shows over 65% of amino acid similarity with the first half of the ...

  3. Acepromazine - Wikipedia

    en.wikipedia.org/wiki/Acepromazine

    Acepromazine. Acepromazine, acetopromazine, or acetylpromazine (commonly known as ACP, Ace, or by the trade names Atravet or Acezine 2, number depending on mg/ml dose) is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic, [4] but is now almost exclusively used on animals as a sedative and ...

  4. Maropitant - Wikipedia

    en.wikipedia.org/wiki/Maropitant

    Maropitant (INN; [2] brand name: Cerenia, used as maropitant citrate (USAN), is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [3][4] and in 2012, for cats. [5]

  5. Multiple drug resistance - Wikipedia

    en.wikipedia.org/wiki/Multiple_drug_resistance

    Multiple drug resistance. Multiple drug resistance (MDR), multidrug resistance or multiresistance is antimicrobial resistance shown by a species of microorganism to at least one antimicrobial drug in three or more antimicrobial categories. [1] Antimicrobial categories are classifications of antimicrobial agents based on their mode of action and ...

  6. Substances poisonous to dogs - Wikipedia

    en.wikipedia.org/wiki/Substances_poisonous_to_dogs

    The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.

  7. Katrina Mealey - Wikipedia

    en.wikipedia.org/wiki/Katrina_Mealey

    While leading a group of WSU researchers, she discovered that a gene mutation called MDR1 predisposed herding dogs—collies to react violently to a deworming pill. Based on this discovery, Mealey developed a clinical test for the mutation based on blood samples and cheek swabs from at least 25 unrelated dogs of every one of the 150-plus breeds.

  8. Diabetes in dogs - Wikipedia

    en.wikipedia.org/wiki/Diabetes_in_dogs

    If left untreated, the condition can lead to cataracts, increasing weakness in the legs (neuropathy), malnutrition, ketoacidosis, dehydration, and death. [2] Diabetes mainly affects middle-aged and older dogs, but there are juvenile cases. [3][4][5] The typical canine diabetes patient is middle-aged, female, and overweight at diagnosis.

  9. Madin-Darby canine kidney cells - Wikipedia

    en.wikipedia.org/wiki/Madin-Darby_Canine_Kidney...

    Madin-Darby canine kidney (MDCK) cells are a model mammalian cell line used in biomedical research. MDCK cells are used for a wide variety of cell biology studies including cell polarity, cell-cell adhesions (termed adherens junctions), collective cell motility, toxicity studies, [1] as well as responses to growth factors.

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