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Yohimbine is an α 2-adrenergic receptor antagonist, and has been used in a variety of research projects. It is a veterinary drug used to reverse sedation in dogs and deer. While yohimbine behaves as an aphrodisiac in some mammals, it does not do so in humans.
[2] [3] Yohimbe bark and extract are used in manufactured dietary supplements, but there is no scientific evidence they have any effect, and yohimbine levels may vary substantially among supplement products. [2] [3] Although proposed as a potential treatment for erectile dysfunction in humans, there are concerns about its safety or effectiveness.
It is a stereoisomer of yohimbine. [1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac. [1] Rauwolscine acts predominantly as a α 2 -adrenergic receptor antagonist. [2][3] It has also been shown to function as a 5-HT 1A receptor partial agonist and 5-HT 2A and 5-HT 2B receptor antagonist. [4][5][6]
Aphrodisiac. An aphrodisiac is a substance alleged to increase libido, sexual desire, sexual attraction, sexual pleasure, or sexual behavior. [1][2][3] These substances range from a variety of plants, spices, and foods to synthetic chemicals. [1][4] Natural aphrodisiacs, such as cannabis or cocaine, are classified into plant-based and non-plant ...
Ajmalicine, also known as δ-yohimbine or raubasine, is an antihypertensive drug used in the treatment of high blood pressure. [1] It has been marketed under numerous brand names including Card-Lamuran, Circolene, Cristanyl, Duxil, Duxor, Hydroxysarpon, Iskedyl, Isosarpan, Isquebral, Lamuran, Melanex, Raunatin, Saltucin Co, Salvalion, and Sarpan. [1]
Atipamezole. Atipamezole , sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2 -adrenergic receptors and displacing them.
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