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US: Schedule II as Syndros, and Schedule III as Marinol [2] Schedule I delta-9 tetrahydrocannabinol in pure form. Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. [9] It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant.
The degradation of D9-THC that forms HHC is the reduction of the double carbon bonds that would typically make up the delta isomer position on THCs structure. [15] [16] Delta-9-THC was discovered to partly metabolize into 11-Hydroxy-THC and alpha,10 alpha-epoxy-hexahydrocannabinol along with 1,2-epoxy-hexahydrocannabinol. [17]
Δ-8-tetrahydrocannabinol (delta-8-THC, [a] Δ8-THC) is a psychoactive cannabinoid found in the Cannabis plant. [1] It is an isomer of delta-9-tetrahydrocannabinol (delta-9-THC, Δ 9 -THC), the compound commonly known as THC, with which it co-occurs in hemp; natural quantities of ∆ 8 -THC found in hemp are low.
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Dronabinol is the INN for delta-9-THC [157] [158] (there is a common confusion according to which the word "dronabinol" would only refer to synthetic delta-9-THC, which is incorrect [159]). Cannabidiol is also the official INN for the molecule, granted in 2017. [160] Nabilone is the INN for a synthetic cannabinoid analog (not present in ...
Tetrahydrocannabinol (THC) is the primary psychoactive component of the Cannabis plant. Delta-9-tetrahydrocannabinol (Δ 9-THC, THC) and delta-8-tetrahydrocannabinol (Δ 8-THC), through intracellular CB 1 activation, induce anandamide and 2-arachidonoylglycerol synthesis produced naturally in the body and brain [citation needed] [dubious ...
Cannabis. A cannabis edible, also known as a cannabis-infused food or simply an edible, is a food item (either homemade or produced commercially) that contains decarboxylated cannabinoids (cannabinoid acids converted to their orally bioactive form) from cannabis extract as an active ingredient. [1] Although edible may refer to either a food or ...
For example, Δ 9-THC has an EC 50 of 250 nM at CB 1 and 1157 nM at CB 2, whereas PB-22 has an EC 50 of 5.1 nM at CB 1 and 37 nM at CB 2. [8] Adverse effects observed due to synthetic cannabinoid use include acute kidney injury , cardiac toxicity , seizure , stroke , tremor , hypokalemia , and rhabdomyolysis .