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Yellapragada Subbarow [a] (12 January 1895 – 8 August 1948) was an Indian American biochemist who discovered the function of adenosine triphosphate (ATP) as an energy source in the cell, [1] developed methotrexate for the treatment of cancer and led the department at Lederle laboratories in which Benjamin Minge Duggar discovered chlortetracycline in 1945.
List of Indian inventions and discoveries; List of Indonesian inventions and discoveries; List of inventions and discoveries of the Indus Valley Civilisation; List of inventions named after people; List of inventors killed by their own invention; Timeline of Irish inventions and discoveries; List of inventions in the medieval Islamic world
Despite advances in technology and understanding of biological systems, drug discovery is still a lengthy, "expensive, difficult, and inefficient process" with low rate of new therapeutic discovery. [6] In 2010, the research and development cost of each new molecular entity was about US$1.8 billion. [7]
Avicenna separates Medicine and Pharmacy, in 1025 published his book The Canon of Medicine, an encyclopedia of medicine formed by five books. Drugs mentioned by Avicenna include agaric, scammony and euphorbium. [19] The latex of Euphorbia resinifera contains resiniferatoxin, an ultra potent capsaicin analog. Desensitization to resiniferatoxin ...
He wrote 30 books on medicine, the "Pandects". He was the first author in antiquity who mentioned the diseases of smallpox and measles [26] translated by MÄsarjawaih a Syrian Jew and Physician, into Arabic about A. D. 683; c. 630 – Paul of Aegina Encyclopedia in 7 books very detailed surgery used by Albucasis [13] [20] [27]
Pharmaceutical innovations are currently guided by a patent system, [1] the patent system protects the innovator of medicines for a period of time. The patent system does not currently stimulate innovation or pricing that provides access to medicine for those who need it the most, It provides for profitable innovation. [2]
Singaporean consumers suffered from misinformation of drug advertisements and lacked standards and qualifications for dispensing drugs. There was also substance abuse with opium and poison accessibility for criminal attempt. This led to creating the Medical Ordinance in 1904 and Poisons Ordinance in 1905 to create standards for qualified ...
AI in drug development successes The world's first COVID-19 drug designed by generative AI is approved for human use, with clinical trials expected to begin in China. The new drug, ISM3312, is developed by Insilico Medicine. [389] A new AI algorithm developed by Baidu is shown to boost the antibody response of COVID-19 mRNA vaccines by 128 ...