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N-Methylacetamide is a flammable, difficult to ignite, hygroscopic, crystalline, colourless solid with a faint odor that is soluble in water. [1] Several isomeric forms are known. [8] [9] In solution, it is 97–100% present as the Z isomer with a polymeric structure. [10] [4] The compound has a high dielectric constant of 191.3 at 32 °C. [11]
4-Acetamidobutanal, also known as N-acetyl-γ-aminobutyraldehyde, N-acetyl-GABAL, or N-acetyl-GABA aldehyde, is a metabolic intermediate in the biosynthesis of γ-aminobutyric acid (GABA) from putrescine.
The related compound N,N-dimethylacetamide (DMA) is more widely used, but it is not prepared from acetamide. Acetamide can be considered an intermediate between acetone, which has two methyl (CH 3) groups either side of the carbonyl (CO), and urea which has two amide (NH 2) groups in those locations.
In chemistry, a zwitterion (/ ˈ t s v ɪ t ə ˌ r aɪ ə n / TSVIT-ə-ry-ən; from German Zwitter 'hermaphrodite'), also called an inner salt or dipolar ion, [1] is a molecule that contains an equal number of positively and negatively charged functional groups. [2] 1,2-dipolar compounds, such as ylides, are sometimes excluded from the ...
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The chemical reactions of dimethylacetamide are typical of N,N-disubstituted amides. Hydrolysis of the acyl-N bond occurs in the presence of acids: CH 3 CON(CH 3) 2 + H 2 O + HCl → CH 3 COOH + (CH 3) 2 NH 2 + Cl −. However, it is resistant to bases. For this reason DMA is a useful solvent for reactions involving strong bases such as sodium ...
Acetamidine hydrochloride is a hygroscopic solid which forms colourless monoclinic crystals. [1] It is soluble in water and alcohol. It releases ammonium chloride upon heating. Dry acetamidine hydrochloride releases acetonitrile, while in aqueous solution, it instead undergoes hydrolysis to acetic acid and ammonia. [3] CH 3 C(NH)NH 2 ·HCl → ...
4-Nitroacetanilide is a chemical compound which is a nitro derivative of acetanilide. There are two other isomers of nitroacetanilide, 2-nitroacetanilide and 3-nitroacetanilide. 4-Nitroacetanilide is used as in intermediate in the production of some dyes .