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In enzymology, a nicotinamide N-methyltransferase (NNMT) (EC 2.1.1.1) is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + nicotinamide ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + 1-methylnicotinamide.
Nicotinamide N-methyltransferase (NNMT) is an enzyme that in humans is encoded by the NNMT gene. [5] NNMT catalyzes the methylation of nicotinamide and similar compounds using the methyl donor S-adenosyl methionine (SAM-e) to produce S-adenosyl-L-homocysteine (SAH) and 1-methylnicotinamide .
NNMT (nicotinamide N-methyltransferase) is an enzyme that in humans is encoded by the NNMT gene. [6] NNMT catalyzes the methylation of nicotinamide and similar compounds using the methyl donor S-adenosyl methionine (SAM-e) to produce S-adenosyl-L-homocysteine (SAH) and 1-methylnicotinamide. [7] NNMT is highly expressed in the human liver. [7]
Dimethylhistidine N-methyltransferase; Glycine N-methyltransferase; Guanidinoacetate N-methyltransferase; Histamine N-methyltransferase; Histone methyltransferase (cytochrome c)-lysine N-methyltransferase (Ribulose-bisphosphate carboxylase)-lysine N-methyltransferase; Methylamine—glutamate N-methyltransferase; Nicotinamide N-methyltransferase ...
This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.
Amine N-methyltransferase (EC 2.1.1.49), also called indolethylamine N-methyltransferase, and thioether S-methyltransferase, is an enzyme that is ubiquitously present in non-neural tissues and catalyzes the N-methylation of tryptamine and structurally related compounds. [1]
The systematic name of this enzyme class is S-adenosyl-L-methionine:nicotinate N-methyltransferase. Other names in common use include furanocoumarin 8-methyltransferase, and furanocoumarin 8-O-methyltransferase. This enzyme participates in nicotinate and nicotinamide metabolism.
NMNH (Dihydronicotinamide mononucleotide), also known as reduced nicotinamide mononucleotide. [1] Both NMNH and NMN increase NAD+ levels in the body. [1] NAD+ is a universal coenzyme that plays vital roles in nearly all living organisms functioning in various biological processes such as metabolism, cell signaling, gene regulation, and DNA repair.